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Sulfur-containing derivatives of β-phenethylamine: Dithiocarbamates and thioureas

✍ Scribed by William O. Foye; Jon C. Anderson

Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
375 KB
Volume
58
Category
Article
ISSN
0022-3549

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✦ Synopsis

0 Ditliiocarbamate and thiourea derivatives of @-phenethylamine, p-4-aminophenethylamine, and their N-substituted derivatives have been synthesized. 1-Methyl-3-phenethylthiourea was found to lower blood pressure significantly in both hypertensive dogs and rats, and the dithiocarbamate of 8-phenethylamine showed hypotensive effects in the dog. Appreciable antifungal activity was also revealed for the latter compound.

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