Sulfonato–Cu(salen) Complex Catalyzed N-Arylation of Aliphatic Amines with Aryl Halides in Water
✍ Scribed by Zhiqing Wu; Li Zhou; Zhaoqiong Jiang; Di Wu; Zhengkai Li; Xiangge Zhou
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 397 KB
- Volume
- 2010
- Category
- Article
- ISSN
- 1434-193X
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## Abstract Pyrrole‐2‐carbohydrazides were synthesized and found to be novel and efficient ligands for the Cu‐catalyzed amination of aryl halides with amines in pure water with high yields. A variety of aryl bromides or iodides could be aminated, promoted by the CuI/__N′__‐phenyl‐1__H__‐pyrrole‐2‐c
## Abstract A combination of CuSO~4~/dimethylglyoxime was found to be an efficient and inexpensive catalyst system for __N__‐arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.