Sulfinyl Moiety as an Internal Nucleophile. 1. Efficient Stereoselective Synthesis of Fragment A of Cryptophycin 3 †
✍ Scribed by Raghavan, Sadagopan; Tony, K. A.
- Book ID
- 126789514
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 96 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
A straightforward and stereospecific synthesis of (+)-polyoxamic acid is disclosed. The key step of the synthesis involves the regio-and stereospecific bromohydration of an olefin via intramolecular participation by the sulfinyl group.
A short, efficient and highly stereoselective synthesis of (-)-(R,R)-muricatacin is reported. The key steps include a highly diastereoselective reduction of a b-ketosulfoxide to a b-hydroxy sulfoxide, regio-and stereoselective bromohydration of an olefin employing the sulfinyl group as an internal n
A novel and stereospecific synthesis of (2R,3S)-3-amino-2-hydroxy-4-phenylbutanoate (AHPBA) is disclosed. The key step includes regio-and stereospecific functionalization of an alkene by the pendant sulfinyl group.
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