Sulfhydryl oxidation and Ca2+release from sarcoplasmic reticulum
โ Scribed by Jonathan J. Abramson; Guy Salamaz
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 317 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0300-8177
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๐ SIMILAR VOLUMES
Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an
The role of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] in excitation-contraction coupling in cardiac muscle is still unclear, although many laboratories are beginning to assume a critical role for this putative second messenger. Earlier studies from this laboratory [Nosek et al. (1986) Am J Physiol
Rapid mixing-vesicle ion flux and planar lipid bilayer-single channel measurements have shown that a high-conductance, ligand-gated Ca2+ release channel is present in 'heavy', junctional-derived membrane fractions of skeletal and cardiac muscle sarcoplasmic reticulum. Using the release channel-speci