Sulfated zirconia; an efficient and reusable acid catalyst for the selective synthesis of 4-phenyl-1,3-dioxane by Prins cyclization of styrene
β Scribed by Marakatti, Vijaykumar S.; Shanbhag, Ganapati V.; Halgeri, A.B.
- Book ID
- 118157073
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 1015 KB
- Volume
- 451
- Category
- Article
- ISSN
- 0926-860X
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## Abstract Polyanilineβsupported TosOH or FeCl~3~ appear to be useful, reusable catalysts for the Prins cyclization of homoallylic alcohols with aromatic aldehydes as well as the synthesis of dioxanes (VIII) via condensation of terminal olefins with paraformaldehyde.
Silica sulfuric acid efficiently catalyzes the three-component Biginelli reaction between an aldehyde, a b-dicarbonyl compound and urea or thiourea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yields. The catalyst is reusable and can be applied several times without