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Sugar Binding Induced Charge Translocation in the Melibiose Permease from Escherichia coli †

✍ Scribed by Meyer-Lipp, Kerstin; Ganea, Constanta; Pourcher, Thierry; Leblanc, Gérard; Fendler, Klaus

Book ID: 127138369
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 104 KB
Volume: 43
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi0489053

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## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 → Cys permease, lactose transport is inactivated by either __N__‐ethy