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Succinate/Amino-Acid Interrelations in Rat Brain Cortex in vitro

✍ Scribed by GONDA, O.; QUASTEL, J. H.

Book ID
109619385
Publisher
Nature Publishing Group
Year
1962
Tongue
English
Weight
328 KB
Volume
193
Category
Article
ISSN
0028-0836

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Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC 50 ) of 0.65 ‫‬ 10 ‫3‬ M. The HCP exerted noncompetitive inhibition at 0.5 mM (Ο½IC 50 ), uncompetitive inhibition at 0.65 mM (IC 50 ), and mixed-type inhibition at 0.