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Successful treatment of cyclic thrombocytopenia with thrombopoietin-mimetic agents: A report of two patients

โœ Scribed by Prithviraj Bose; Khader K. Hussein; Deirdra R. Terrell; Dietmar Berger; Lawrence Rice; James N. George

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
418 KB
Volume
84
Category
Article
ISSN
0361-8609

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โœฆ Synopsis

therefore, accelerating the endothelial turnover. Although the increase in EPCs number in our study did not reach statistical significance, it is a well-known fact that PB EPCs are extremely rare and their mobilization takes place hours after the application of the stimulus, whereas in this study the blood was drawn after about 10 min after the goal of the exercise test was achieved.

Our observations on the effects of exercise on the CECs may help to explain the benefits that exercise has on the cardiovascular system, suggesting a role of mechanical factors such as BP on the endothelial renewal in physiological conditions.

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Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrom