Cytogenetic investigation of a malignant ovarian tumor diagnosed as a mixed germ-cell tumor, composed of extensive choriocarcinoma and foci of yolk-sac tumor, revealed a highly abnormal chromosomal pattern. We found a chromosome number in the hypertriploid/hypotetraploid range, and several clonal st
Successful chemotherapeutic decompression of epidural malignant germ cell tumor
โ Scribed by Gale, Gordon B. ;O'Connor, Dennis M. ;Chu, Jen-Yih ;Tantana, Supranee ;Weber, Thomas R.
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 496 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
A patient with a sacrococcygeal malignant germ cell tumor developed epidural spinal cord compression syndrome 32 days after surgical resection of tumor. Rapid resolution of symptoms was observed after chemotherapy with vinblastine, bleomycin, and cisplatinum. There was no radiation therapy or laminectomy for spinal compression. The patient had an excellent neurological recovery without any sequelae from spinal compression. Chemotherapy alone is an excellent approach to the management of epidural compression by malignant germ tumor.
๐ SIMILAR VOLUMES
Three sisters in a family with seven children whose grandmother had an ovarian embryonal carcinoma experienced development of malignant and a malignant-like situation in childhood. Two were diagnosed as having malignant germ cell tumors of the ovary, and the third was found to have Langerhans' histi
## Background: Brain metastases of pediatric germ cell tumors are uncommon, and there is limited information regarding their incidence, clinical presentation, response to treatment, and influence on survival. ## Methods: The authors reviewed the experience with brain metastases from pediatric ger