Subtelomeric Microduplications in Three Sisters with Moderate Mental Retardation
✍ Scribed by Lamia Hila; Hedia Tébourbi; Leila Abeid; Imen Rejeb; Habiba Chaabouni
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 139 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0006-2928
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## Communicated by Ulf Landegren Subtelomeric rearrangements are responsible for 5% to 10% of cases of unexplained mental retardation. Despite their clinical relevance, methods to screen for these cytogenetically invisible abnormalities on a routine base are scarce. We screened patients with idiopa
Nonspecific X-linked mental retardation (XLMR) is a common disorder. The number of genes involved in this condition is not known, but it is estimated to be more than 10. We present a clinical and linkage study on 3 families with XLMR. All families were analyzed using highly polymorphic markers cover