Increasing the sialylation of therapeuti
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Kaya Bork; Rüdiger Horstkorte; Wenke Weidemann
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Article
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2009
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John Wiley and Sons
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English
⚖ 240 KB
The number of therapeutic proteins has increased dramatically over the past years and most of the therapeutic proteins in the market today are glycoproteins. Usually, recombinant glycoproteins are produced in mammalian cell lines, such as Chinese-hamster-ovary-cells to obtain mammalian-type of glyco