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Parasite-Specific Inhibition of the Glycosylphosphatidylinositol Biosynthetic Pathway by Stereoisomeric Substrate Analogues †

✍ Scribed by Smith, Terry K.; Paterson, Michael J.; Crossman, Arthur; Brimacombe, John S.; Ferguson, Michael A. J.


Book ID
126223605
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
116 KB
Volume
39
Category
Article
ISSN
0006-2960

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Parasite Glycoconjugates. Part 7. Synthesis of Further Substrate Analogues of Early Intermediates in the Biosynthetic Pathway of Glycosylphosphatidylinositol Membrane Anchors. -Compounds (Ia)-(Ic) are prepared for biological evaluation with the α-(1 → 4)-Dmannosyltransferase of the protozoan parasi