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Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver

โœ Scribed by PJ Meier; U Eckhardt; A Schroeder; B Hagenbuch; B Stieger

Book ID
118686781
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
306 KB
Volume
26
Category
Article
ISSN
0270-9139

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๐Ÿ“œ SIMILAR VOLUMES

Substrate specificity of sinusoidal bile
Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver
โœ P J Meier; U Eckhardt; A Schroeder; B Hagenbuch; B Stieger ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 295 KB

The Na+-dependent bile salt uptake systems Ntcp (rodents) and NTCP (human), and the Na+-independent organic anion transporters oatpl (rat) and OATP (human) mediate sinusoidal uptake of a variety of amphipathic organic compounds into hepatocytes. Their properties indicate that an overall hepatic clea