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Substrate Specificity of Mutants of the Hydroxynitrile Lyase from Manihot esculenta

✍ Scribed by Holger Bühler; Franz Effenberger; Siegfried Förster; Jürgen Roos; Harald Wajant


Book ID
101820982
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
142 KB
Volume
4
Category
Article
ISSN
1439-4227

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✍ Holger Bühler; Burkhard Miehlich; Franz Effenberger 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 216 KB

## Abstract __The influence of Trp128‐substituted mutants of the hydroxynitrile lyase from__ Manihot esculenta __(MeHNL) on the stereoselectivity of MeHNL‐catalyzed HCN additions to aldehydes with stereogenic centers, which yield the corresponding cyanohydrins, is described. In__ rac__‐2‐phenylprop