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Substrate selectivity of the steroid dehydrogenase of Arthrobacter simplex. Its use for the resolution and determination of absolute and relative configuration in total synthesis

โœ Scribed by Fried, Josef.; Green, Michael John.; Nair, G. V.


Book ID
127109864
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
273 KB
Volume
92
Category
Article
ISSN
0002-7863

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Total synthesis of pinellic acid, a pote
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Pinellic acid (1), isolated from a medicinal plant Pinelliae tuber, has potent adjuvant activity. The absolute configuration of pinellic acid was expected by derivatization of this compound and CD exciton chirality method. A convergent synthetic route to pinellic acid has been developed via regiosel