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Substrate model for the activation of nitrosamines by cytochrome P450

✍ Scribed by G. Moeckel; B. Spiegelhalder; H. Bartsch; W. Heiden; J. Brickmann

Book ID
112784566
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
157 KB
Volume
121
Category
Article
ISSN
1432-1335

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## Abstract Cytochrome P450 (CYP) is an important drug‐metabolizing enzyme family. Different CYPs often have different substrate preferences. In addition, one drug molecule may be preferentially metabolized by one or more CYP enzymes. Therefore, the classification and prediction of substrate specif