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Substrate entropy in enzyme enantioselectivity: An experimental and molecular modeling study of a lipase

โœ Scribed by Jenny Ottosson; Linda Fransson; Karl Hult


Book ID
119824650
Publisher
Cold Spring Harbor Laboratory Press
Year
2002
Tongue
English
Weight
191 KB
Volume
11
Category
Article
ISSN
0961-8368

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## Abstract Based on the highโ€resolution Xโ€ray crystallographic structure of phospholipase C from __Bacillus cereus__, the orientation of the phosphatidylcholine substrate in the active site of the enzyme is proposed. The proposal is based on extensive calculations using the GRID program and molecu