✦ LIBER ✦

Substitution reactions of 17.alpha.-vinyl-17.beta.-trifluoroacetoxy steroids

✍ Scribed by Ortar, Giorgio; Morera, Enrico; Romeo, Aurelio

Book ID: 126140987
Publisher: American Chemical Society
Year: 1978
Tongue: English
Weight: 317 KB
Volume: 43
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo00408a043

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Allylic rearrangement of 17.alpha.-vinyl

Allylic rearrangement of 17.alpha.-vinyl-17.beta.-hydroxy steroids

✍ Olsen, Douglas O.; Babler, James H. 📂 Article 📅 1975 🏛 American Chemical Society 🌐 English ⚖ 359 KB

Cardenolide analogs. 9. Synthesis and bi

Cardenolide analogs. 9. Synthesis and biological activity of 17.beta.-carbomethoxyethylene and 17.beta.-cyanoethylene 14.alpha.-H steroids

✍ Gelbart, Alex; Boutagy, John; Thomas, Richard 📂 Article 📅 1979 🏛 American Chemical Society 🌐 English ⚖ 568 KB

ChemInform Abstract: Nucleophilic Vinyli

ChemInform Abstract: Nucleophilic Vinylic “Addition-Elimination” Substitution Reaction of 3. beta.-Acetoxy-17-chloro-16-formylandrosta-5,16-diene: A Novel and General Route to 17-Substituted Steroids. Part 1. Synthesis of Novel 17-Azolyl-δ16 Steroids; Inhibitors of 17α-Hydroxylase/17, 20-Lyase (17α-Lyase).

✍ V. C. O. NJAR; G. T. KLUS; A. M. H. BRODIE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Pentacyclic steroids. Synthesis of 4,6.b

Pentacyclic steroids. Synthesis of 4,6.beta.-ethanoestradiol, 4,6.beta.-ethanoestrone, and 17.alpha.-ethynyl-4,6.beta.-ethanoestradiol

✍ Ghosh, Anil C.; Hazra, Braja G.; Duax, William L. 📂 Article 📅 1977 🏛 American Chemical Society 🌐 English ⚖ 553 KB

Substitution and elimination reactions o

Substitution and elimination reactions of steroid tertiary C-17 trifluoroacetates

✍ Ortar, Giorgio.; Romeo, Aurelio. 📂 Article 📅 1976 🏛 American Chemical Society 🌐 English ⚖ 453 KB

Nucleophilic vinylic “addition-eliminati

Nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene: A novel and general route to 17-substituted steroids. Part 1 - synthesis of novel 17-azolyl-Δ16 steroids; inhibitors of 17α-hydroxylase/17, 20-lyase (17α-lyase)

✍ Vincent C.O. Njar; Gregory T. Klus; Angela M.H. Brodie 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 283 KB

We have discovered that chlorine in 3~-acetoxy-17-chloro-16-formylandrosta-5,16-diene (1) can be smoothly displaced by nitrogen heterocyclic nucleophiles (her) to give heretofore unknown 17-substituted-A t6 steroids in high yields (73-92%). This enabled us to synthesize novel 3~-hydroxy-17-(1H-1,2,4