The syntheses of four 4-methyl-4-phenyl-l,2,3,4-tetrahydro-Znaphthoic acids are described. The stereospecific cyclization of the cis-isomers and proton NMR studies establishing cistrans product ratios are also reported. Keyphrases 0 Tetralins, substituted-synthesis, stereochemistry of 4,4-disubstit
Substituted tetralins VI: Tentative assignment of absolute stereochemistry of 1-methyl-1-phenyl-1,2,3,4-tetrahydro-3-naphthoic acid and N,N,1-Trimethyl-1-phenyl-1,2,3,4-tetrahydro-3-naphthylamine Isomers
β Scribed by D. R. Galpin; E. M. Kandeel; A. R. Martin
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 508 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The complete and unambiguous assignment of the 1H NMR and 13C NMR spectra of 26 N-aralkylsulfonamides, N-sulfonyl-1,2,3,4-tetrahydroisoquinolines and N-sulfonylbenz[c]azepines was performed on the basis of APT, DEPT, homonuclear (gs-COSY) and 1H-detected heteronuclear one-bond (gs-HMQC) and long-ran
1,2,3,6-Tetrahydr0-4-[U-1~C]phenylpyridine (12) was synthesized and coupled to (R)-3-phenyl-3-cyclohexene-1-carboxylic acid to make the titled compound 2 in 21% overall yield. Purification considerations were an important factor in the choice of a reaction sequence to 2, and successful synthesis was