𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Substituted spiro [2.3′] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

✍ Scribed by Mohamed Ashraf Ali; Rusli Ismail; Tan Soo Choon; Yeong Keng Yoon; Ang Chee Wei; Suresh Pandian; Raju Suresh Kumar; Hasnah Osman; Elumalai Manogaran

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
278 KB
Volume
20
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.

✦ Synopsis

Series of pyrolidine analogues were synthesized and examined as acetylcholinesterase (AChE) inhibitors. Among the compounds, compounds 4k and 6k were the most potent inhibitors of the series. Compound

📜 SIMILAR VOLUMES

Synthesis of 2,6-diamino-5-[(2-substitut
Synthesis of 2,6-diamino-5-[(2-substituted phenylamino)ethyl]pyrimidin-4(3h)-one as inhibitors of folate metabolizing enzymes
✍ Aleem Gangjee; Ying Wang; Sherry F. Queener; Roy L. Kisliuk 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 562 KB

## Abstract magnified image A series of eleven novel 2,6‐diamino‐5‐[(2‐substituted phenylamino)ethyl]pyrimidin‐4(3__H__)‐one derivatives were synthesized as potential inhibitors of dihydrofolate reductase (DHFR) and thymidylate synthase (TS). The synthesis of analogues **2a‐f, 3a** and **3e** was

Asymmetric Synthesis of 1,2,3,4,5,6-Hexa
Asymmetric Synthesis of 1,2,3,4,5,6-Hexahydro-5-hydroxypyrimidin-2-ones as Potential HIV-Protease Inhibitors
✍ Dieter Enders; Lars Wortmann; Barbara Dücker; Gerhard Raabe 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 German ⚖ 101 KB 👁 1 views

The first asymmetric synthesis of potential cyclic urea HIV protease inhibitors of Type 2 is reported. The synthesis is short and highly versatile in the choice of the substitution pattern and absolute configuration of the products starting from readily available materials. Nonchiral central buildin