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Substituted oxindoles. III. Synthesis and pharmacology of some substituted oxindoles

✍ Scribed by Walker, John; Daisley, Roy W.; Beckett, Arnold H.


Book ID
127098832
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
455 KB
Volume
13
Category
Article
ISSN
0022-2623

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A new synthesis of 3-aryl substituted ox
✍ Thi-My Ly; Nieves M Laso; Samir Z Zard πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 677 KB

A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate ; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride.