✦ LIBER ✦

A new synthesis of 3-aryl substituted oxindoles

✍ Scribed by Thi-My Ly; Nieves M Laso; Samir Z Zard

Book ID: 104208515
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 677 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(98)00172-0

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✦ Synopsis

A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate ; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride.

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