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Laccase-catalyzed 3-Arylation of 3-Substituted Oxindoles

✍ Scribed by Prof. Dr. Jörg Pietruszka; Dr. Chuan Wang


Book ID
112019316
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
228 KB
Volume
4
Category
Article
ISSN
1867-3880

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A new synthesis of 3-aryl substituted ox
✍ Thi-My Ly; Nieves M Laso; Samir Z Zard 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 677 KB

A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate ; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride.