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Substituted 1,3,2,4-benzodithiadiazines and related compounds

✍ Scribed by Irina Yu. Bagryanskaya; Yuri V. Gatilov; Alexander Yu. Makarov; Alexander M. Maksimov; Alexey O. Miller; Makhmut M. Shakirov; Andrey V. Zibarev

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
342 KB
Volume
10
Category
Article
ISSN
1042-7163

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✦ Synopsis

The preferred direction of cyclization is consistent with thermodynamics of the corresponding intermediate r-complexes as well as factors of kinetic control for an orbital-controlled El-Nu reaction.

According to the X-ray diffraction data, the molecules of 5-CF 3 ( 15) and 6-F ( 12) derivatives are nearly planar, while the molecules of 5-OCH 3 ( 7) and 6-CH 3 (4) derivatives are bent along the S 1 . . . N 4 line by ϳ11Њ

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Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds
✍ V. K. Tandon; Meenu Vaish; J. M. Khanna; Nitya Anand πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 227 KB

Series of (1.4)-Naphthoquinono(3,2-c>lH-pyrazoles and 2-substituted amino-1.4-naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Wulker 256 carcinosarmma). MluenZa RNA tmnscriptase activity, ,antibiotic activity (C. neoformans, T. mentagraphytes