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Substance P-induced histamine release from rat peritoneal mast cells and its inhibition by antiallergic agents and calmodulin inhibitors

โœ Scribed by Mitsunobu Mio; Keiji Izushi; Kenji Tasaka


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
603 KB
Volume
22
Category
Article
ISSN
0162-3109

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In rat peritoneal mast cells induced by anti-immunoglobulin E, ciwujianosides D1 (1) and C1 (2) from Acanthopanax senticosus (ciwujia) strongly inhibited histamine release in a concentration-dependent manner. The inhibitory effect of 1 was approximately 6800 times stronger than that of disodium crom