Substance P (SP)-ergic neurons from 16/17 day-embryonic rat brain stem in primary culture were identified by immunocytochemistry using biotinylated avidine and phosphatase alcaline methods with affinity-purified anti-SP antibodies. An average of 84% of neurons contained SP from day 9 to day 21 after
Substance P immunoreactivity in the major pelvic ganglion of the rat
โ Scribed by Dail, William G. ;Dziurzynski, Rene
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 752 KB
- Volume
- 212
- Category
- Article
- ISSN
- 0003-276X
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Primary afferent neurons containing substance P (SP) are apparently implicated in the transmission of noxious information from the periphery to the central nervous system, and SP released from primary afferent neurons acts on second-order neurons with the SP receptor (SPR). In the rat, nociceptive i
Intracellular electrophysiological recordings were made in vitro at 36.5 degrees C from lumbar (L4 to L6) dorsal root ganglion neurones of 6-8-week-old female rats. Electrophysiological properties were recorded prior to intracellular injection with fluorescent dye. The following showed substance P-l