𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Subclassification of microsatellite-unstable tumors in colorectal cancer

✍ Scribed by Nita Ahuja; Stephen B. Baylin

Book ID
107535676
Publisher
Current Science Inc.
Year
2007
Tongue
English
Weight
265 KB
Volume
3
Category
Article
ISSN
1556-3790

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Beta2-microglobulin mutations in microsa
Beta2-microglobulin mutations in microsatellite unstable colorectal tumors
✍ Matthias Kloor; Sara Michel; Boris Buckowitz; Josef RΓΌschoff; Reinhard BΓΌttner; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 362 KB

## Abstract Defects of DNA mismatch repair (MMR) cause the high level microsatellite instability (MSI‐H) phenotype. MSI‐H cancers may develop either sporadically or in the context of the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome that is caused by germline mutations of MMR genes. In

Immune evasion of microsatellite unstabl
Immune evasion of microsatellite unstable colorectal cancers
✍ Matthias Kloor; Sara Michel; Magnus von Knebel Doeberitz πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 385 KB

## Abstract Colorectal cancers (CRC) develop through 2 major pathways of genetic instability. In contrast to the majority of CRCs, which are characterized by chromosomal instability, high‐level microsatellite unstable (MSI‐H) CRCs arise as a consequence of the loss of DNA mismatch repair (MMR) func

BRAF mutations in colorectal carcinoma s
BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors
✍ Nikolaus Lubomierski; Guido Plotz; Marc Wormek; Knut Engels; Susanne Kriener; Jo πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 285 KB πŸ‘ 1 views

## Abstract ## BACKGROUND Alterations of __BRAF__ have been implicated in the carcinogenesis of colorectal tumors with microsatellite instability (MSI). These alterations were attributed to defective DNA mismatch repair, which underlies MSI. It was the objective of this study to clarify the role o