Diets containing antimony trioxide were fed to male and female Wistar rats of the Alpk:APSD strain over 90 days. Dose levels were 0 (control), 1000, 5000 and 20,000 ppm (equivalent to mean daily doses of 84, 421 and 1686 mg kg(-1) in males and 97, 494 and 1879 mg kg(-1) in females). There was no eff
Subchronic feeding study in rats of immobilized lactase following in utero exposure
β Scribed by Peter J. Becci; Larry A. Gephart; Thomas A. Re
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 320 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0260-437X
No coin nor oath required. For personal study only.
β¦ Synopsis
The effect of subchronic feeding of immobilized lactase composite following in utero exposure was studied in Sprague-Dawley rats. The dose levels of immobilized lactase composite that were used were 25, 100 and 400 mg per kg body weight per day. Reproduction performance, body weight gain and food consumption, organ weight, hematological and clinical chemical data, and ophthalmic, gross and histopathological examinations were used to study possible toxicological or pathological effects. No treatment-related effects were observed in either male or female rats exposed to immobilized lactase composite at any dose level.
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