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Subcellular localisation of cyclin B, Cdc2 and p21WAF1/CIP1 in breast cancer: association with prognosis

✍ Scribed by Z.E Winters; N.C Hunt; M.J Bradburn; J.A Royds; H Turley; A.L Harris; C.J Norbury


Book ID
117657424
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
309 KB
Volume
37
Category
Article
ISSN
0959-8049

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p21WAF1/Cip1 is associated with cyclin D
✍ Rey, Maria J.; FernΓ‘ndez, Pedro L.; Jares, Pedro; MuΓ±oz, Montserrat; Nadal, Alfo πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 406 KB πŸ‘ 2 views

p21 WAF1/Cip1 is an inhibitor of cdk/cyclin complexes, and thus regulates the cell cycle. p21 is also related to cell differentiation and is regulated by wild-type p53, although p53-independent regulatory pathways have been proposed. In order to analyse p21 expression as well as its relationship wit