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Subacute sclerosing panencephalitis antibodies against measles virus polypeptides

โœ Scribed by D. Karcher; H. Thormar; A. Lowenthal; M. Noppe

Book ID
104717853
Publisher
Springer
Year
1982
Tongue
English
Weight
434 KB
Volume
227
Category
Article
ISSN
0340-5354

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โœฆ Synopsis

Antibodies to measles virus proteins in SSPE, MS and control human sera were compared using measles virus strain Edmonston, productive SSPE strain Mantooth and non-productive SSPE strain DR. The viral antigens were subjected to transfer electrophoresis, incubated with sera and localized after a second incubation with peroxidase labeled immunoglobulins. High levels of antibodies to all measles viral proteins are present in SSPE sera and CSF and to a lesser degree in MS and control sera although the non-productive SSPE strains lack one viral protein (M protein) present in wild type measles virus strains and the productive SSPE strains.

๐Ÿ“œ SIMILAR VOLUMES

Measles antibodies in the saliva of chil
Measles antibodies in the saliva of children with subacute sclerosing panencephalitis
โœ W. Sobczyk; I. Polna; J. Kulczycki; H. Horbowska ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 189 KB

Using the method of haemagglutination inhibition, the authors determined the levels of measles antibodies in the saliva of 14 children with subacute sclerosing panencephalitis. In 13 of them these antibodies were found in titres from 1:8 to 1:128. In the control groups, comprising 29 children, these