Differences between the intracellular polypeptides of measles and subacute sclerosing panencephalitis virus
โ Scribed by WECHSLER, STEVEN L.; FIELDS, BERNARD N.
- Book ID
- 109709066
- Publisher
- Nature Publishing Group
- Year
- 1978
- Tongue
- English
- Weight
- 589 KB
- Volume
- 272
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/272458a0
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๐ SIMILAR VOLUMES
A cytopathic measles virus was isolated from a brain biopsy of a subacute sclerosing panencephalitis (SSPE) patient. The agent could be transferred to Vero cells by cocultivation, but the infectivity always remained cell-associated -ie, a defective virus infection. The cell-associated nature of the
Significantly higher CSF titers of hemagglutination (HI) measles virus antibody were found in 22 patients with subacute sclerosing panencephalitis (SSPE) and more elevated titers of measles virus neutralization (NV) antibody were encountered in 19 patients with SSPE than in 50 children and young adu
Subacute sclerosing panencephalitis, a rare, progressive, fatal central nervous system disease of children, is caused by measles virus. Clinical signs occur months to several years after recovery from acute measles infection. It is not known where the virus persists while the disease is inapparent.