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Su1340 Detection of Colorectal Cancer and Polyps in Patients With Inflammatory Bowel Disease by Novel Methylated Stool DNA Markers

✍ Scribed by Kisiel, John B.; Taylor, William R.; Allawi, Hatim; Yab, Tracy C.; Simonson, Julie A.; Devens, Mary E.; Lowrie, Kari L.; Boardman, Lisa A.; Smyrk, Thomas C.; Lidgard, Graham P.; Mahoney, Douglas W.; Ahlquist, David A.

Book ID
122267814
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
553 KB
Volume
146
Category
Article
ISSN
0016-5085

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In most cases the analysis of DNA mutations in presence of a high excess of wild type DNA fail because of the low sensitivity of the performed method for mutation detection. Here we describe the new high-sensitive and non-radioactive HD-PCR method (for HeteroDuplex-PCR). In opposite to the conventio