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Study on the interaction between photodynamic therapy and a PI3K pathway inhibitor

โœ Scribed by B. Chen; B. Fateye

Book ID
116823347
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
70 KB
Volume
8
Category
Article
ISSN
1572-1000

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โœ Yanzhong Zhang; E. Zachary Oblak; Erin S.D. Bolstad; Amy C. Anderson; Jerry P. J ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 485 KB

The natural product liphagal has been shown to function as a reasonably potent and selective inhibitor of the key signaling enzyme PI-3Ka. We have been interested in developing an analog class of PI-3K inhibitors based upon this unusual terpenoid natural product. Toward that end, we have evaluated t