Study on the antioxidant activity of cholesteryl esters of some phenolic acids by chemiluminescence

✍ Scribed by Zhetcho D. Kalitchin; Margarita I. Boneva; Tsenka Milkova; Daniela Todorova

• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Weight: 404 KB
• Volume: 41
• Category: Article
• ISSN: 1011-1344
• DOI: 10.1016/s1011-1344(97)00090-0

✦ Synopsis

Four cholesteryl esters of cinnamic acid derivatives, cholesteryl 2"-hydroxycinnamate, cholesteryl 3"-hydroxycinnamate, cho]esteryl 4"-hydroxy-cimmmate and cholesteryl 3",4"-dihydroxycinnamate, as well as cholestanyl 2"-hydroxycinnamate. which can be used as p~emial inhibitors of l ipids oxidation, have been investigated for their radical scavenging efficiency by a chemilumine~ence metl,ax]. The rate constants of inhibition (kmH) were determined in a model reaction of an initiated oxidation of tetraline at 353 K.

The cbemiluminescent results show that the four cholesteryl esters are efficient radical acceptors, and that among them, chole~ery| 3"~4"-dihydr~xycinnamateisaparticu~ar~ye~cientradica~scavengerwithaninhibiti~nratec~nstant~f~.8~ IOSdm 3 tool ~ s-~.