Study on porous silk fibroin materials. II. Preparation and characteristics of spongy porous silk fibroin materials

✍ Scribed by Mingzhong Li; Zhengyu Wu; Changsheng Zhang; Shenzhou Lu; Haojing Yan; Dong Huang; Huilan Ye

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 312 KB
• Volume: 79
• Category: Article
• ISSN: 0021-8995
• DOI: 10.1002/1097-4628(20010321)79:12<2192::aid-app1027>3.0.co;2-0

✦ Synopsis

Porous silk fibroin materials, with average pore size 10 ϳ 300 m, pore density 1 ϳ 2000/mm 2 , and porosity 35 ϳ 70%, were prepared by freeze drying aqueous solution of silk fibroin obtained by dissolving silk fibroin in ternary solvent CaCl 2 ⅐ CH 3 CH 2 OH ⅐ H 2 O. Pore size distribution of such materials mostly accorded with logarithmic normal distribution. It is possible to control the aforementioned structural parameters and the physical properties of moisture permeability, compressibility, strength, elongation, etc., by adjusting freezing temperature and concentration of silk fibroin solution. Above glass transition zone (Ϫ34 ϳ Ϫ20°C) of silk fibroin, the freezing temperature has more significant effect on the structure and properties of porous silk fibroin materials.