Study on porous silk fibroin materials. I. Fine structure of freeze dried silk fibroin

✍ Scribed by Mingzhong Li; Shenzhou Lu; Zhengyu Wu; Haojing Yan; Jingyu Mo; Lihong Wang

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 170 KB
• Volume: 79
• Category: Article
• ISSN: 0021-8995
• DOI: 10.1002/1097-4628(20010321)79:12<2185::aid-app1026>3.0.co;2-3

✦ Synopsis

Silk fibroin solution was prepared by dissolving the silk fibroin in triad solvent CaCl 2 ⅐ CH 3 CH 2 OH ⅐ H 2 O. In this article we tested and analyzed the state of frozen silk fibroin solution and fine structure of freeze dried porous silk fibroin materials. The results indicated that the glass transition temperature of frozen silk fibroin solution ranges from Ϫ34 to Ϫ20°C, and the initial melting temperature of ice in frozen solution is about Ϫ8.5°C. When porous silk fibroin materials are prepared by means of freeze drying, if freezing temperature is below Ϫ20°C, the structure of silk fibroin is mainly amorphous with a little silk II crystal structure, and if freezing temperature is above Ϫ20°C, quite a lot of silk I crystal structure forms.