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Study of the solid-state hydrogen isotope exchange ofl-alanine

✍ Scribed by Yu. A. Zolotarev; E. V. Laskatelev; V. S. Kozik; E. M. Dorokhova; S. G. Rozenberg; Yu. A. Borisov; N. F. Myasoedov

Publisher
Springer
Year
1997
Tongue
English
Weight
498 KB
Volume
46
Category
Article
ISSN
1573-9171

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## Abstract Solid state catalytic hydrogen isotope exchange has been employed to label hen egg lysozyme with tritium. Optimization of reaction conditions so that amino acids and peptide bonds remained intact led to a tritiated product with 97% of the original enzymatic activity and 94% radiochemica