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Study of solid-state catalytic isotope exchange of hydrogen inl-hydroxyproline under the action of spillover tritium

โœ Scribed by Yu. A. Zolotarev; Yu. A. Borisov


Publisher
Springer
Year
1999
Tongue
English
Weight
357 KB
Volume
48
Category
Article
ISSN
1573-9171

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## Abstract Solid state catalytic hydrogen isotope exchange has been employed to label hen egg lysozyme with tritium. Optimization of reaction conditions so that amino acids and peptide bonds remained intact led to a tritiated product with 97% of the original enzymatic activity and 94% radiochemica