Preliminary studies have shown a very high inhibitory activity in the alpha a and gamma zone of human serum towards the growth of Cryptococcus neoformans. These findings are now corroborated by single radial immunodiffusion tests, which showed the some loss of IgA and IgM globulins and of the other
Study of the role of iron in the anticryptococcal activity of human serum and fluconazole
โ Scribed by Devina D. Grover; Elmer Brummer; David A. Stevens
- Publisher
- Springer Netherlands
- Year
- 1996
- Tongue
- English
- Weight
- 475 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0301-486X
No coin nor oath required. For personal study only.
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The growth requirements of three human leukemic cell lines (K 562, HEL, U937) have been studied in the absence of serum. For growth in serum-free medium, the cells require insulin, transferrin, and albumin. Two highly watersoluble iron salts, ferric ammonium citrate and ferric ammonium sulfate, may
## Abstract Iron, an essential growth trace element, is required for proliferation of all living cells, including T lymphocytes. Many, though not all, immune responses require lymphocyte proliferation. Iron deficiency, a worldwide public health problem for children and for women of childbearing age