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Study of the Rearrangements of Oxonium Ylides Generated from Ketals

โœ Scribed by Brogan, John B.; Zercher, Charles K.; Bauer, Cary B.; Rogers, Robin D.


Book ID
126082634
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
289 KB
Volume
62
Category
Article
ISSN
0022-3263

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Tetmhydrofumn-3-ones and tetrahydropymrr-3-ones can be prepmedenrmtiosekxtively by rearrangementof the ylide-typeintermediatesgeneratedby the reactionof a chiral copper carbenoidwith the oxygenatom of a pendant allylic ether. Cyclic ethers with enantiomericexcesses of up to 57% have been obtainedusi