Study of the influence of nifedipine on the pharmacokinetics and pharmacodynamics of propranolol, metoprolol and atenolol.
β Scribed by D Gangji; M Juvent; G Niset; M Wathieu; M Degreve; R Bellens; J Poortmans; S Degre; TJ Fitzsimons; A Herchuelz
- Book ID
- 117943481
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 777 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0306-5251
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This double-blind randomized, crossover study was undertaken to determine the pharmacokinetic properties of nifedipine retard and atenolol when given separately, as a free or a fixed combination, compared with placebo in 15 healthy male volunteers. There was no difference between the three atenolol
The influence of inflammatory disease on the pharmacokinetics of atenolol and metoprolol was investigated after administering single oral 100 mg doses of the drugs to six subjects. Each subject had a respiratory tract infection with an erythrocyte sedimentation rate (ESR) of over 20 mm in the first