𝔖 Bobbio Scriptorium
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Study of mechanisms of peripheral tolerance by T cell receptor transgenic mice

✍ Scribed by Diana Zelenika; Steve P. Cobbold; Andrew L. Mellor; Elisabeth Simpson; Herman Waldman


Book ID
108409015
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
180 KB
Volume
56
Category
Article
ISSN
0165-2478

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Antigen-specific T cell tolerance can be induced by systemic injection of high-dose antigen. In particular, a single intravenous (i.v.) injection of influenza virus hemagglutinin peptide in HNT-TCR transgenic mice induces T cell tolerance through thymocyte apoptosis as well as anergy and deletion of