Studies with Polyfunctionally Substituted Heteroaromatics: A Novel Synthesis of Substituted 4,8-Diaminoisoquinolines as Potential Antiparasitic Agents
โ Scribed by Al-Omran, Fatima; El-Khair, Adel Abou; Elnagdi, Mohammed Hilmy
- Book ID
- 120218861
- Publisher
- Science Reviews 2000 Ltd
- Year
- 1998
- Tongue
- English
- Weight
- 131 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0308-2342
- DOI
- 10.1039/A804639E
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The 1-substituted ethylidenemalononitriles la-c condensed with triethyl orthoformate in refluxing acetic anhydride to yield the dienes 2a-c. On the other hand, a mixture o f N, N-dimethylformamide and triethyl orthoformate condensed with la-d to yield the N, N-dimethylaminopentadienonitriles 2d-g. T
The reactions of formaldehyde and acetaldehyde with active methylene compounds, followed by reaction with cyanoacetic acid hydrazide 2, afforded N-aminopyridine-2-one derivatives 5a-f. In contrast, the reactions of cyanoacetic acid hydrazide 2 with aliphatic aldehydes and cyanothioacetamide afforded