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ChemInform Abstract: Studies with Polyfunctionally Substituted Heteroaromatics: A Facile Route for the Synthesis of Polyfunctionally Substituted N- Aminopyridines, 1,2,4-Triazolo(1,5-a)pyridines and Isoquinolines.

โœ Scribed by A. H. M. HUSSEIN


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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Studies with polyfunctionally substitute
โœ Abdel Haleem Mostafa Hussein ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 187 KB ๐Ÿ‘ 2 views

The reactions of formaldehyde and acetaldehyde with active methylene compounds, followed by reaction with cyanoacetic acid hydrazide 2, afforded N-aminopyridine-2-one derivatives 5a-f. In contrast, the reactions of cyanoacetic acid hydrazide 2 with aliphatic aldehydes and cyanothioacetamide afforded