The synthesis of the BCDE-tetracyclic core of (-)-cephalotaxine has been achieved in eight steps starting from N-Boc-L-proline methyl ester. An alkylidene carbene 1,5-CH insertion reaction was used as a key step in the stereocontrolled synthesis of the DE-spirocyclic fragment and an intramolecular H
β¦ LIBER β¦
Studies towards the total synthesis of lycoposerramine A. Synthesis of a model for the tetracyclic core
β Scribed by Elliott, Mark C.; Paine, James S.
- Book ID
- 118739294
- Publisher
- Royal Society of Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 207 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1477-0520
- DOI
- 10.1039/B909860G
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