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Studies toward the total synthesis of the hirsutellones

✍ Scribed by Mingzheng Huang; Chong Huang; Bo Liu


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
390 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


A strategy of tandem ketene-trapping/IMDA toward the total synthesis of the hirsutellones was attempted. The AB ring moiety of the hirsutellones was constructed with the proper stereochemistry.


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Total Synthesis of Hirsutellone B
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Hirsutellones, [1] pyrrospirones, [2] and pyrrocidines [3] belong to a growing class of fungal secondary metabolites whose biological properties include antifungal and antibiotic activities.

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## Abstract For Abstract see ChemInform Abstract in Full Text.

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