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Studies on the total synthesis of the saponaceolides. 1. Enantioselective synthesis of the spiroketal subunit

โœ Scribed by Giovanni Vidari; Gianluigi Lanfranchi; Natalina Pazzi; Stefano Serra

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
214 KB
Volume
40
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

An asymmetric synthesis of the tricyclic spiroketal subunit of the saponaceolides is described in which the absolute stereochemistry at C-2' and C-6' is established through a conformationally and stereoelectronically controlled cyclization ofa dihydroxyketone pyran intermediate.

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