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Studies on the Synthesis of Fungitoxic Pterocarpans: 1. Synthesis of 6a-Hydroxy-11a-Methylpterocarpan

✍ Scribed by Dervilla M. X. Donnelly, P. J. Gunning and M. J. Meegan


Book ID
124171985
Publisher
Royal Irish Academy
Year
1977
Weight
688 KB
Volume
77
Category
Article
ISSN
0035-8983

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A general synthesis of 8-hydroxy-6-subst
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## Abstract magnified image A general method for the synthesis of 8‐hydroxy‐6‐substituted‐1,7‐naphthyridines is described using acylation of the dianion derived from __tert__‐butylamide **1**, followed by cyclization of the resulting intermediate ketones **2** with ammonium acetate.