Studies on the synthesis of strychnos in
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Mercedes Alvarez; Rodolfo Lavilla; Joan Bosch
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Article
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1987
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Elsevier Science
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French
⚖ 279 KB
A short, new route to the title tetracyclic substructure of Sf/cycho4 alkaloids, consisting in the nucleophilic attack of an ester a-anion to a pyridinium salt, acid-induced cyclization of the resultant 1,4\_dihydropyridine, and stereospecific elaboration of the ethylidene substituent, is reported.