The reaction of isoquinoline and dimethy
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Vijay Nair; A.R Sreekanth; A.T Biju; Nigam P Rath
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Article
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2003
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Elsevier Science
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French
β 221 KB
The 1,4-dipolar intermediate generated by the addition of isoquinoline to dimethyl acetylenedicarboxylate is trapped by 1,2-and 1,4-benzoquinones to afford spiro[1,3]oxazino[2,3-a]isoquinoline derivatives in high yields.